Ultrasound Irradiation Promoted Enzymatic Transesterification of (R/S)-1-Chloro-3-(1-naphthyloxy)-2-propanol
نویسندگان
چکیده
منابع مشابه
Ultrasound irradiation promoted enzymatic transesterification of (R/S)-1-chloro-3-(1-naphthyloxy)-2-propanol.
(R)-1-Chloro-3-(1-naphthyloxy)-2-propanol, which is the key intermediate of (S)-propranolol, was successfully prepared via enantioselective transesterification catalyzed by lipase under ultrasound irradiation. Compared with conventional shaking, the enzyme activity and enantioselectivity were dramatically increased under ultrasound exposure. Effects of various reaction conditions on the synthet...
متن کاملReproductive toxicology. 1-Chloro-2-propanol.
1 Department of Bioengineering, University of California San Diego, La Jolla, CA, USA and 2 Institute for Nonlinear Science, University of California San Diego, La Jolla, CA, USA 3 These authors contributed equally to this work 4 Present address: Institute for Systems Biology, Seattle, WA 98103, USA * Corresponding author. Department of Bioengineering, University of California San Diego, 9500 G...
متن کامل(3-Aminophenyl)diphenylphosphine oxide–2-propanol (1/1)
The title compound, C(18)H(16)NOP·C(3)H(8)O, was synthesized by the reduction of (3-nitro-phen-yl)diphenyl-phosphine oxide in the presence of 2-propanol as recrystallization solvent. There are two molecules in the asymmetric unit. Each P atom is tetra-coordinated by three C and one O atom from two phenyl fragments, one aniline group and one double-bonded O atom in a distorted tetra-hedral geome...
متن کامل1-{6-Chloro-2-[(2-chloro-3-quinolyl)methoxy]-4-phenyl-3-quinolyl}ethan-1-one
In the title compound, C(27)H(18)Cl(2)N(2)O(2), the 2-chloro-quinoline and 6-chloro-quinoline rings are almost planar, with maximum deviations from their mean planes of 0.072 (1) and 0.044 (1) Å, respectively, for the Cl atoms. The inter-planar angle between these rings is 14.36 (5)°. The inter-planar angle between the 6-chloro-quinoline and phenyl rings is 66.00 (8)°. In the crystal, mol-ecule...
متن کاملSynthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles
A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n) using 2-amino-4phenyl-1, 3-thiazole as a starting material. The synthesised compounds have been screened in vitro for their antimicrobial acti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecules
سال: 2012
ISSN: 1420-3049
DOI: 10.3390/molecules170910864