Unfixed cryosections of striated muscle to study dynamic molecular events
نویسندگان
چکیده
منابع مشابه
Dynamic Regulation of Sarcomeric Actin Filaments in Striated Muscle
In striated muscle, the actin cytoskeleton is differentiated into myofibrils. Actin and myosin filaments are organized in sarcomeres and specialized for producing contractile forces. Regular arrangement of actin filaments with uniform length and polarity is critical for the contractile function. However, the mechanisms of assembly and maintenance of sarcomeric actin filaments in striated muscle...
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An electrostatic mechanism for force generation in muscle is proposed which does not require bond formation between thick and thin filaments nor movement of the cross bridges. The myosin heads, which project from the thick filaments and touch the thin filaments, possess a high negative surface charge density. Owing to their large dielectric increment, the thin filaments are polarized by the ele...
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The unidirectional fluxes of sodium, chloride, anid potassium across the mnembrane of striated muscle cells are described under a number of experiniental conditions. The results are compared with the predicted behavior of simple membranes. With the possible exception of chloride, it is concluded that the movements of these ions cannot be described without postulating variable permeabilities or ...
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The musculature of the telson of Limulus polyphemus L. consists of three dorsal muscles: the medial and lateral telson levators and the telson abductor, and one large ventral muscle; the telson depressor, which has three major divisions: the dorsal, medioventral, and lateroventral heads. The telson muscles are composed of one type of striated muscle fiber, which has irregularly shaped myofibril...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1994
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(94)80634-4