Unsupported Copper Nanoparticles in the Arylation of Amines

Commercially available copper and (II) oxide nanoparticles (CuNPs CuO NPs) were characterized using TEM electronography methods to elucidate their true average size composition. The catalytic amine arylation unsupported differing in oxidation state was investigated. reaction of the model iodobenzene with n-octylamine shown be successfully catalyzed by CuNPs 25 10/80 nm presence ligands such as 2-isobutyrylcyclohexanone (L1) rac-1,1′-bi-2-naphthol (BINOL, L2), giving high yields (up 95%) target N-octylaniline. bulk nano forms almost equally efficient this process. Studies on Cu-catalyzed amination substituted iodobenzenes 2-iodopyridine, well different aliphatic amines NH-heterocycles, verified that (25 or nm) L1 L2 are most versatile nanocatalysts for a variety substrates. Investigation leaching under conditions carried out.