Ureaplasma parvum causes hyperammonemia in a pharmacologically immunocompromised murine model

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Ureaplasma urealyticum Causes Hyperammonemia in an Experimental Immunocompromised Murine Model

Hyperammonemia syndrome is an often fatal complication of lung transplantation which has been recently associated with Ureaplasma infection. It has not been definitely established that Ureaplasma species can cause hyperammonemia. We established a novel immunocompromised murine model of Ureaplasma urealyticum infection and used it to confirm that U. urealyticum can cause hyperammonemia. Male C3H...

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BACKGROUND Ureaplasmas are among the most common bacteria isolated from the human urogenital tract. Ureaplasmas can produce asymptomatic infections or disease characterized by an exaggerated inflammatory response. Most investigations have focused on elucidating the pathogenic potential of Ureaplasma species, but little attention has been paid to understanding the mechanisms by which these organ...

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ژورنال

عنوان ژورنال: European Journal of Clinical Microbiology & Infectious Diseases

سال: 2016

ISSN: 0934-9723,1435-4373

DOI: 10.1007/s10096-016-2827-1