Urinary Transforming Growth Factor-.BETA.1 in Feline Chronic Renal Failure
نویسندگان
چکیده
منابع مشابه
Urinary active transforming growth factor β in feline chronic kidney disease
The cytokine transforming growth factor beta 1 (TGF-β1) has been widely implicated in the development and progression of renal fibrosis in chronic kidney disease (CKD) in humans and in experimental models. The aims of this study were to assess the association between urinary active TGF-β1 and (a) development of CKD in a cross-sectional study, (b) deterioration of renal function over 1 year in a...
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Matrix accumulation in the renal tubulointerstitium is predictive of a progressive decline in renal function. Transforming growth factor-beta(1) (TGF-beta(1)) and, more recently, connective tissue growth factor (CTGF) are recognized to play key roles in mediating the fibrogenic response, independently of the primary renal insult. Further definition of the independent and interrelated effects of...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2005
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.67.1253