Use of Intra-arterial Thrombolytic Therapy for Acute Treatment of Frostbite in 62 Patients with Review of Thrombolytic Therapy in Frostbite

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Use of Intra-arterial Thrombolytic Therapy for Acute Treatment of Frostbite in 62 Patients with Review of Thrombolytic Therapy in Frostbite

Amputations are common after severe frostbite injuries, often mediated by postinjury arterial thrombosis. Since 1994, the authors have performed angiography to identify perfusion deficits in severely frostbitten digits and treated these lesions with intraarterial infusion of thrombolytic agents, usually combined with papaverine to reduce vasospasm. A retrospective review was performed of patien...

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Reduction of the incidence of amputation in frostbite injury with thrombolytic therapy.

HYPOTHESIS Thrombolytic therapy will decrease the incidence of amputation when administered within 24 hours of exposure. DESIGN Single institution retrospective review of clinical outcomes and resource use. SETTING Burn unit of a tertiary academic referral center. PATIENTS From 2001 to 2006, patients with severe frostbite admitted within 48 hours of injury underwent digital angiography an...

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Safety and feasibility of intravenous thrombolytic therapy in Iranian patients with acute ischemic stroke

  Background: Thrombolytic therapy is the only approved treatment for acute cerebral ischemia. The hemorrhagic transformation is the greatest complication of this treatment, which may occur after recanalization of occluded artery. The aim of this study was to determine factors associated with clinical improvement and worsening in patients with acute ischemic stroke treated with intravenous th...

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Intra-Arterial Thrombolytic Therapy for Acute Basilar Occlusion

Acute thromboembolic occlusion of the basilar artery accounts for 6% to 10% of large-vessel stroke in humans. Because of the brain region supplied by this artery, the case fatality rate is the highest for all ischemic stroke subtypes, ranging from 40% to 86%. Patients who undergo successful recanalization of the basilar artery by intra-arterial thrombolysis have lower mortality of 39%. Consider...

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ژورنال

عنوان ژورنال: Journal of Burn Care & Research

سال: 2016

ISSN: 1559-047X

DOI: 10.1097/bcr.0000000000000245