Use of phosphorothioate analogs of poly(dA-dT) · poly(dAdT) to study steroidal-diamine induced conformational change in poly(dA-dT) · poly(dA-dT)
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Conformational transitions of poly(dA-dT)poly(dA-dT) in ethanolic solutions.
Examination of circular dichroic and phosphorus nuclear magnetic resonance spectra showed that poly(dA-dT)-poly(dA-dT) exhibited an ethanol-induced transition to the A form in an Na+ containing medium like natural DNAs. A mere replacement of the Na+ by Cs+ counterions meant that the polynucleotide was with a little cooperativity transformed into a novel conformation displaying a deep negative b...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1985
ISSN: 0014-5793
DOI: 10.1016/0014-5793(85)80845-0