Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement
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چکیده
منابع مشابه
Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement
BACKGROUND & PURPOSE Allogenic blood transfusion in elective orthopaedic surgery is best avoided owing to its associated risks. Total knee replacement often requires blood transfusion, more so when bilateral surgery is performed. Many strategies are currently being employed to reduce the amount of peri-operative allogenic transfusions. Anti-fibrinolytic compounds such as aminocaproic acid and t...
متن کاملWhich Route of Tranexamic Acid Administration is More Effective to Reduce Blood Loss Following Total Knee Arthroplasty?
Background: The most appropriate route of tranexamic acid administration is controversial. In the current study, we compared the efficacy of intravenous (IV) and topical intra-articular tranexamic acid in reducing blood loss and transfusion rate in patients who underwent primary total knee arthroplasty. Methods: One hundred twenty 120 patients were scheduled to undergo primary total knee arth...
متن کاملTranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement.
BACKGROUND Total knee arthroplasty (TKA) is often carried out using a tourniquet and shed blood is collected in drains. Tranexamic acid decreases the external blood loss. Some blood loss may be concealed, and the overall effect of tranexamic acid on the haemoglobin (Hb) balance is not known. METHODS Patients with osteoarthrosis had unilateral cemented TKA using spinal anaesthesia. In a double...
متن کاملThe Efficacy of Intravenous Versus Topical Use of Tranexamic Acid in Reducing Blood Loss after Primary Total Knee Arthroplasty: A Randomized Clinical Trial
Background: Blood loss during and immediately after total knee arthroplasty (TKA) is among the most challenging concerns. It has been demonstrated that Tranexamic acid (TXA) can help to reduce perioperative blood loss. TXA can be used as an oral, topical or intravenous injection. Many studies evaluated the effectiveness of each route of administration but few works on a comparison between them....
متن کاملUse of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
We have investigated the effect of treatment with tranexamic acid, an inhibitor of fibrinolysis, on blood loss, blood transfusion requirements and blood coagulation in a randomized, double-blind, placebo-controlled study of 42 patients after total knee arthroplasty. Tranexamic acid 15 mg kg-1 (n = 21) or an equivalent volume of normal saline (n = 21) was given 30 min before surgery and subseque...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Surgery and Research
سال: 2011
ISSN: 1749-799X
DOI: 10.1186/1749-799x-6-22