Validity of serology for American Trypanosomiasis with eluates from filter paper

Evaluation of Mycobacterium leprae particle agglutination test, using eluates of filter paper blood spots.

A comparison of the ELISA test with the newly-developed MLPA test was carried out, using eluates of blood spots from filter paper for the detection of the anti-PGL-I antibody. A very good positive correlation was observed between these two tests. The concordance rate was found to be 92.6%, ranging from 71.4% to 100%. This nonconcordance was not found when freshly-collected samples were used. Th...

American trypanosomiasis (Chagas disease).

Chagas disease, also known as American trypanosomiasis, is a chronic infection caused by Trypanosoma cruzi, a protozoan parasite. It is transmitted to human beings mainly through the feces of infected triatomine bugs. The disease affects an estimated 8 to 10 million people in the Americas, putting them at risk of developing life-threatening cardiac and gastrointestinal complications. This artic...

American Trypanosomiasis (Chagas Disease)

American trypanosomiasis (Chagas disease) is an important cause of human heart disease, megaesophagus and megacolon in Latin America, where the causative organism, Trypanosoma cruzi, is endemic. While this organism occasionally causes an acute illness, most people do not realize they are infected until several years or decades later, when some develop a chronic medical condition. Antiparasitic ...

The Agglutinatiun Test with Brucella Sera Absorbed into Filter Paper

WHO | Chagas disease (American trypanosomiasis)

An estimated 10 million people are infected with Trypanosoma cruzi (the parasite that causes Chagas disease) worldwide, mostly in Latin America. Chagas disease was once entirely confined to the Region of the Americas – principally Latin America – but it has now spread to other continents. Chagas disease is curable if treatment is initiated soon after infection. Up to 30% of chronically infected...