Vascular Reactivity in Experimental Hypertension Measured after Hexamethonium

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Vascular reactivity in experimental hypertension measured after hexamethonium.

ONE of the few observations made in hypertension upon which there is almost universal agreement is the increased response of the blood pressure to pressor drugs. It is found in nearly all types of hypertension, both experimentally and clinical.>9 Nevertheless, the mechanisms responsible for it have not been adequately investigated. I have studied the vascular reactivity in rabbits, comparing th...

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Vascular Reactivity in Experimental Hypertension Measured after Hexamethonium

ONE of the few observations made in hypertension upon which there is almost universal agreement is the increased response of the blood pressure to pressor drugs. It is found in nearly all types of hypertension, both experimentally and clinical.>9 Nevertheless, the mechanisms responsible for it have not been adequately investigated. I have studied the vascular reactivity in rabbits, comparing th...

متن کامل

Vascular Reactivity in Experimental Hypertension Measured after Hexamethonium

ONE of the few observations made in hypertension upon which there is almost universal agreement is the increased response of the blood pressure to pressor drugs. It is found in nearly all types of hypertension, both experimentally and clinical.>9 Nevertheless, the mechanisms responsible for it have not been adequately investigated. I have studied the vascular reactivity in rabbits, comparing th...

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Increased vascular reactivity in experimental hypertension.

• The etiology of essential hypertension is unknown. Its pathogenesis is also not clear, but it is generally agreed that the basic defect is an excessive resistance to blood flow due to a diminished internal caliber of arterial vessels, especially of the systemic arterioles. Implicit in this concept is the idea that a compensatory action of the heart occurs, the heart beating more forcibly so t...

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Vascular reactivity in hypertension.

IN ESTABLISHED human hypertension, there has never been any real doubt that the baroreceptor mechanisms remain active, hut regulate the arterial pressure to a new high level. The upward setting of these baroreeeptors occurs not only in essential hypertension but also in hypertension secondary to renal disease of various sorts. There is also evidence from the effects of ganglion blocking drugs t...

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ژورنال

عنوان ژورنال: Circulation

سال: 1958

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.17.4.807