Vascular tissue engineering: structure versus function
نویسندگان
چکیده
منابع مشابه
Overview on Vascular Tissue Engineering: Progress and Challenges
Today, vascular diseases such as atherosclerosis are one of the leading causes of death in the world and the prevalence of it in older societies is rising. The current treatments for repair of cardiovascular function include organ transplantation, surgical reconstruction, mechanical or artificial devices, or the use of metabolic products. Although these methods are commonly used, they did not g...
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The fields of vascular biology and vascular medicine are so intertwined that advances in one predict, explain, or are required for progress in the other. Bypass grafting, which once served as a “bailout” procedure,1,2 is now performed more than 600 000 times annually in the United States. In major part, this increase can be attributed to a surge in understanding of the vascular response to inju...
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Tissue engineering of vascular grafts 187 1 3 Summary Background There is a considerable clinical need for a sufficient prosthetic small-diameter substitute which can compete with autologous vessels. Currently used synthetic materials have a poor performance due to high thrombogeneicity and development of intimal hyperplasia. Tissue engineering is an interesting alternative approach for vascula...
متن کاملTransmural flow bioreactor for vascular tissue engineering.
Nutrient transport limitation remains a fundamental issue for in vitro culture of engineered tissues. In this study, perfusion bioreactor configurations were investigated to provide uniform delivery of oxygen to media equivalents (MEs) being developed as the basis for tissue-engineered arteries. Bioreactor configurations were developed to evaluate oxygen delivery associated with complete transm...
متن کاملTissue engineering of small diameter vascular grafts.
Tissue engineering, using either polymer or biological based scaffolds, represents the newest approach to overcoming limitations of small diameter prosthetic vascular grafts. Their disadvantages include thromboembolism and thrombosis, anticoagulant related haemorrhage, compliance mismatch, neointimal hyperplasia, as well as aneurysm formation. This current review represents an overview about pr...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2000
ISSN: 0741-5214
DOI: 10.1016/s0741-5214(00)90125-3