Vilazodone in the treatment of major depressive disorder
نویسندگان
چکیده
منابع مشابه
Vilazodone in the treatment of major depressive disorder: efficacy across symptoms and severity of depression
Vilazodone is a potent selective serotonin reuptake inhibitor and serotonin 1A receptor partial agonist approved for the treatment of major depressive disorder in adults. To assess the efficacy of vilazodone across a range of symptoms and severities of depression, data from two phase III, 8-week, randomized, double-blind, placebo-controlled trials were pooled for analysis. Overall improvement i...
متن کاملThe Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder.
INTRODUCTION Major depressive disorder (MDD) is the leading cause of disability worldwide, and according to the STAR*D trial, only 33% of patients with MDD responded to initial drug therapy. Augmentation of the leading class of antidepressant treatment, selective serotonin reuptake inhibitors (SSRIs), with the 5-HT1A receptor agonist buspirone has been shown to be effective in treating patients...
متن کاملVortioxetine versus placebo for treatment of major depressive disorder
Introduction: Major depressive disorder is a common mental condition associated with substantial morbidity and economic burden. Approved by the FDA in September 2013 for treatment of episodes of major depressive disorder, Vortioxetine is one of the newer options available in this important area of therapeutics. Materials and methods: A comprehensive literature search (PubMed, the Cochrane libr...
متن کاملVilazodone for the treatment of major depressive disorder: an evidence-based review of its place in therapy
INTRODUCTION It has clearly been demonstrated that depressive disorders constitute a major worldwide public health problem, with massive economic and quality-of-life consequences. Existing pharmacological treatments have limited efficacy, with only about a third of patients achieving remission on any one medication. Delayed onset of action and variable tolerability contribute to this limited ef...
متن کاملEvaluation of the efficacy and safety of vilazodone for treating major depressive disorder
PURPOSE Vilazodone is a novel serotonin (5-HT)-reuptake inhibitor and 5-HT1A partial agonist that was recently developed for the treatment of major depressive disorder (MDD). We conducted a meta-analysis and systematic review to better evaluate the efficacy and safety of vilazodone. MATERIALS AND METHODS We performed a thorough literature search to identify all randomized double-blind placebo...
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ژورنال
عنوان ژورنال: International Clinical Psychopharmacology
سال: 2014
ISSN: 0268-1315
DOI: 10.1097/yic.0000000000000016