Viral dynamics of HIV-1 with CTL immune response
نویسندگان
چکیده
In this paper, we investigate an in-host model for the viral dynamics of HIV-1 infection and its interaction with CTL immune response. The is sufficiently general to allow nonlinear forms both Threshold parameters are identified that completely determine global outcomes virus-target cell-CTL interactions. Impacts key parameter values functions budding rate on load CD4 count investigated using numerical simulations. Results support clinical evidence important differences between nonprogressors progressors.
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ژورنال
عنوان ژورنال: Discrete and Continuous Dynamical Systems-series B
سال: 2021
ISSN: ['1531-3492', '1553-524X']
DOI: https://doi.org/10.3934/dcdsb.2020212