Vital Microscopy of Bone Remodelling in Rabbit Ear Chambers

The growth of bone autografts in rabbit ear chambers.

Transparent regenerative chambers similar to the type originally developed by Sandison (1928), Kirby-Smith (1933) and Clark and Clark (1942), but with slight modifications of our own (Ezra 1966, 1967) were implanted in the central portion of the pinna (Fig. I). The table of the chamber was well vascularised and ready for bone implantation in three weeks. Autogenous bone was obtained from the sp...

Observations on Tissue Grafts Established in Rabbit Ear Chambers

An in vivo microscopic and ultrastructural study of tissues transferred to the transparent rabbit ear chamber is presented. Fragments of liver, kidney, thyroid, and myometrium were successfully auto- or allografted into the chamber from donors of all ages and allowed continuous in vivo observation of parenchymal structure and function, as well as of the graft vasculature which plays such an act...

Bone Remodelling in BioShape

Many biological phenomena are inherently multiscale, i.e. they are characterised by interactions involving different scales at the same time. This is the case of bone remodelling, where macroscopic behaviour (at organ and tissue scale) and microstructure (at cell scale) strongly influence each other. Consequently, several approaches have been defined to model such a process at different spatial...

Bone Structure and Bone Remodelling

Detection and Localization of Drosophila Egg Chambers in Microscopy Images

Drosophila melanogaster is a well-known model organism that can be used for studying oogenesis (egg chamber development) including gene expression patterns. Standard analysis methods require manual segmentation of individual egg chambers, which is a difficult and time-consuming task. We present an image processing pipeline to detect and localize Drosophila egg chambers that consists of the foll...