Vitamin D supplementation and serum neurofilament light chain in interferon‐beta‐1b‐treated MS patients
نویسندگان
چکیده
منابع مشابه
Serum neurofilament light chain in relapsing-remitting MS
MS is a chronic disease of the CNS, well recognized for its diverse clinical presentations and outcomes. Clinicians continue to struggle to predict shortor long-term prognosis of persons affected by MS, to predict response to the growing array of diseasemodifying treatments available, and to identify persons at risk of serious adverse events from those treatments. As such, valid, reliable, and ...
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Background: Multiple sclerosis (MS) is a chronic disease characterized by inflammation and degeneration of the central nervous system (CNS). High levels of Neurofilament light chain (NFL) and Neurofilament heavy chain (NFH) in cerebrospinal fluid (CSF) have been associated with a wide range of neurological diseases including MS. Subjects and methods: Peripheral blood samples were collected from...
متن کاملNeurofilament light chain predicts disease activity in relapsing-remitting MS
Objective To investigate whether serum neurofilament light chain (NF-L) and chitinase 3-like 1 (CHI3L1) predict disease activity in relapsing-remitting MS (RRMS). Methods A cohort of 85 patients with RRMS were followed for 2 years (6 months without disease-modifying treatment and 18 months with interferon-beta 1a [IFNB-1a]). Expanded Disability Status Scale was scored at baseline and every 6 ...
متن کاملSerum Vitamin D Concentrations in CoVID19 Patients
Background and purpose: Vitamin D deficiency is highly prevalent in Iran. Death toll due to the Coronavirus Disease 2019 (COVID-19) is high in this country. The purpose of the present investigation was to provide more information on the relationship between serum levels of vitamin D in confirmed cases of COVID-19 in north of Iran. Materials and methods: This cross-sectional descriptive study w...
متن کاملNeurofilament light chain
Objective: To test blood and CSF neurofilament light chain (NfL) levels in relation to disease progression and survival in amyotrophic lateral sclerosis (ALS). Methods: Using an electrochemiluminescence immunoassay, NfL levels were measured in samples from 2 cohorts of patients with sporadic ALS and healthy controls, recruited in London (ALS/control, plasma: n 5 103/42) and Oxford (ALS/control,...
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ژورنال
عنوان ژورنال: Brain and Behavior
سال: 2020
ISSN: 2162-3279,2162-3279
DOI: 10.1002/brb3.1772