Wasp Venom Possesses Potential Therapeutic Effect in Experimental Models of Rheumatoid Arthritis
نویسندگان
چکیده
منابع مشابه
Effect of bee venom on experimental arthritis.
Stimulation of cells and tissues, whether by mechanical, hormonal, or neurological means, results in the increased biosynthesis of prostaglandins (Ramwell and Shaw, 1970). It has been suggested that one such stimulus is inflammation, in the course of which phospholipases are freed from the lysosomes of phagocytes. These enzymes can cleave phospholipids of the cell membrane to yield arachidonic ...
متن کاملWasp venom allergy: effect of anti-IgE antibody on wasp venom anaphylaxis in a mouse model.
BACKGROUND Although anti-IgE antibody (Ab) therapy was recently shown to be effective in patients with bronchial asthma, no study has reported the effect of IgE therapy in the prevention of wasp venom anaphylaxis. In this study, we used a mouse model of wasp venom allergy to investigate the effect of anti-IgE Ab on wasp venom anaphylaxis. METHODS We developed a mouse model of wasp venom aller...
متن کاملTherapeutic effects of lornoxicam-loaded nanomicellar formula in experimental models of rheumatoid arthritis
BACKGROUND Rheumatoid arthritis (RA) is a chronic inflammatory disease treated by nonsteroidal anti-inflammatory drugs (NSAIDs) including lornoxicam (LX). Nanocarriers have been used to increase the efficacy and reduce the side effects of various drugs. The objective of the present study was to compare the therapeutic efficacy of systemic administration of lornoxicam-loaded nanomicellar formula...
متن کاملAdiponectin isoforms: a potential therapeutic target in rheumatoid arthritis?
OBJECTIVES Several clinical studies have suggested the adipocytokine adiponectin is involved in the progression of rheumatoid arthritis (RA). From this point of view, adiponectin might present a new therapeutic target. However, as adiponectin also exerts beneficial effects in the human organism, a strategy that would allow its detrimental effects to be abolished while maintaining the positive e...
متن کاملTherapeutic Potential of Snake Venom
Annually 2.5 million people are bitten by snakes, more than 100,000 fatally. In India a large no of people suffer and die every year due to snake venom poisoning. Venom has been used in the treatment of a variety of pathophysiological conditions in Ayurveda, homeopathy and folk medicine. Snake venom is a natural biological resource, containing a complex mixture of enzymes, peptides and protein ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2020
ISSN: 1741-427X,1741-4288
DOI: 10.1155/2020/6394625