What's it all worth?

Tolerance--is it worth it?

We are entering an exciting time in the study of immunologic tolerance. Several cellular and molecular strategies have been developed that show promise in nonhuman transplant models and these approaches are just now appearing in clinical trials. Tolerance strategies that prevent immune rejection and obviate the need for immunosuppressive medications (with inherent risk of cancer, infection, and...

Test them all, is it worth it? A ground truth comparison of configuration sampling strategies

Many approaches for testing configurable software systems start from the same assumption: it is impossible to test all configurations. This motivated the definition of variability-aware abstractions and sampling techniques to cope with large configuration spaces. Yet, there is no theoretical barrier that prevents the exhaustive testing of all configurations by simply enumerating them, if the ef...

Is It Worth Arguing?

Argumentation-based negotiation (ABN) is an effective means of resolving conflicts in a multi-agent society. However, it consumes both time and computational resources for agents to generate, select and evaluate arguments. Furthermore, in many cases, argumentation is not the only means of resolving conflicts. Thus, some could be avoided either by finding an alternative means (evading the confli...

Imaging of parathyroid lesions with radionuclides - Is it worth doing?

Parathyroid adenomas, or hyperplasia may be present in patients with hypercalcemia. Treatment Is by surgical excision, but about 10% of the lesions may be In ectopic locations. Pre-operative localization of the lesions with non-lvasive imaging, using radionuclides, ultrasound, CT, or MR], may simplify surgery, and reduce patient morbidity. However, the reports of the accuracy of the curre...

Getting a Mba: Is It worth It?