Which azithromycin regimen should be used for treating Mycoplasma genitalium? A meta-analysis

Persistence of Mycoplasma genitalium Following Azithromycin Therapy

BACKGROUND To determine clinical outcomes and cure rates for M.genitalium genital infection in men and women following azithromycin 1 g. METHODOLOGY Patients attending Melbourne Sexual Health Centre between March 2005 and November 2007 with urethritis/epididymitis, cervicitis/pelvic inflammatory disease and sexual contacts of M.genitalium were tested for M.genitalium by polymerase chain react...

Azithromycin Failure in Mycoplasma genitalium Urethritis

We report significant failure rates (28%, 95% confidence interval 15%-45%) after administering 1 g azithromycin to men with Mycoplasma genitalium-positive nongonococcal urethritis. In vitro evidence supported reduced susceptibility of M. genitalium to macrolides. Moxifloxacin administration resulted in rapid symptom resolution and eradication of infection in all cases. These findings have impli...

Should Steroids Be Used in Treating Bronchiolitis?

640 SHOULD STEROIDS BE USED IN TREATING BRONCHIOLITIS? S INCE their introduction into clinical use, corticosteroids have been employed as therapeutic agents in virtually every known disease state, ranging from minor dermatologic disorders to major and serious diseases. These agents have undoubtedly altered the clinical picture and prognosis of certain diseases. However, the use of corticosteroi...

Should Steroids Be Used in Treating Bronchiolitis?

640 SHOULD STEROIDS BE USED IN TREATING BRONCHIOLITIS? S INCE their introduction into clinical use, corticosteroids have been employed as therapeutic agents in virtually every known disease state, ranging from minor dermatologic disorders to major and serious diseases. These agents have undoubtedly altered the clinical picture and prognosis of certain diseases. However, the use of corticosteroi...

Which treatment option should be used?