WHO pulls two generic AIDS drugs from approved list

The use of essential drugs. Model list of essential drugs (seventh list). Fifth report of the WHO Expert Committee.

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WHO admits its target on AIDS drugs may be unrealistic.

Examining non-AIDS mortality among people who inject drugs

OBJECTIVE To systematically review and analyse data from cohorts of people who inject drugs (PWID) to improve existing estimates of non-AIDS mortality used to calculate mortality among PWID in the Spectrum Estimates and Projection Package. DESIGN Systematic review and meta-analysis. METHODS We conducted an update of an earlier systematic review of mortality among PWID, searching specificall...

12 myths about HIV/AIDS and people who use drugs.

People who use drugs too often face stigma, discrimi­ nation, and mistreatment in HIV prevention, treatment, and care. Some societies consider such users less deserving of compassion than others with HIV who are not drug users, because users' health problems are self­inflicted or their substance use is judged as a moral or personal failing. Even among health­care providers, many preconceptions ...

Identification of Non-Electrophilic Nrf2 Activators from Approved Drugs.

Oxidative damage can lead to a wide range of diseases. Nrf2 is an important transcription factor that regulates many of the cytoprotective enzymes involved in the oxidative stress response. Therefore, targeting the regulation of Nrf2 activation is one logical and effective strategy to prevent or lower the risk of oxidative stress-related diseases. Until now, most research has focused on electro...