Why Doesn’t Primary Biliary Cholangitis Respond to Immunosuppressive Medications?
نویسندگان
چکیده
منابع مشابه
Why Doesn’t Primary Biliary Cholangitis Respond to Immunosuppressive Medications?
PURPOSE OF REVIEW The purpose of this review is to discuss reasons why immunosuppressive therapy so far failed in Primary Biliry Cholangitis. RECENT FINDINGS Even targeted immunosuppressive therapy seems ineffective or potentially harmful. SUMMARY Bile acid-mediated cholangiocyte damage, facilitated by insufficient bicarbonate secretion, seems to attenuate the anti-inflammatory and anti-fib...
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ژورنال
عنوان ژورنال: Current Hepatology Reports
سال: 2017
ISSN: 2195-9595
DOI: 10.1007/s11901-017-0345-y