Wildtype and A30P Mutant Alpha-Synuclein Form Different Fibril Structures
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چکیده
منابع مشابه
Wildtype and A30P Mutant Alpha-Synuclein Form Different Fibril Structures
Parkinson's Disease (PD) is a neurodegenerative movement disorder affecting millions of people worldwide. One of the key players in the development of the disease is the protein α-synuclein (aSN), which aggregates in the brain of PD patients. The aSN mutant A30P has been reported to cause early-onset familial PD and shows different aggregation behavior compared to wt aSN. Here we use a multidis...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0067713