Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth
نویسندگان
چکیده
منابع مشابه
Tunicamycin inhibits mouse tooth morphogenesis and odontoblast differentiation in vitro.
Tunicamycin (TM), an antibiotic that selectively inhibits dolichol-mediated protein glycosylation, inhibited morphogenesis and differentiation of odontoblasts in the molar tooth germ in vitro. These effects of TM are reversible and dose-dependent, and in advanced teeth the effect of TM was not complete unless the basement membrane was removed prior to culture. TM did not prevent secretion of pr...
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From the Department of Oral Histology-Developmental Biology, Dental Research Institute, Conservative Dentistry, **Oral & Maxillofacial Surgery, and Tooth Bioengineering National Research Lab, School of Dentistry, Seoul National University, Seoul 110-749, Korea and the Department of Biochemistry and the Program in Neuroscience, School of Medicine and Biomedical Science, and the Department of Ora...
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During development, precise temporal and spatial gradients are responsible for guiding axons to their appropriate targets. Within the developing ventral midbrain (VM) the cues that guide dopaminergic (DA) axons to their forebrain targets remain to be fully elucidated. Wnts are morphogens that have been identified as axon guidance molecules. Several Wnts are expressed in the VM where they regula...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2011
ISSN: 1058-8388
DOI: 10.1002/dvdy.22550