Worming into host immune responses
نویسندگان
چکیده
منابع مشابه
Host innate immune responses to sepsis
The immune response to sepsis can be seen as a pattern recognition receptor-mediated dysregulation of the immune system following pathogen invasion in which a careful balance between inflammatory and anti-inflammatory responses is vital. Invasive infection triggers both pro-inflammatory and anti-inflammatory host responses, the magnitude of which depends on multiple factors, including pathogen ...
متن کاملHow Some Mycoplasmas Evade Host Immune Responses
E ven though free-living, mycoplasmas depend on their hosts for key nutrients, including purines, pyrimidines, several amino acids, and sterols, which are incorporated into the membranes of these wall-less bacteria. These requirements reflect their relative genomic simplicity. The 580-kb genome of Mycoplasma genitalium, for example, is comparable in size to that of a large virus. Nonetheless, t...
متن کاملHost Immune Responses Against Pulmonary Fungal Pathogens
The lungs are a gateway for numerous airborne pathogens that are ubiquitous in our environment. Among these potential pathogens are fungi that can be found in the soil, bird excreta, air ducts, and many other places where their contact is unavoidable. Exposure to these fungal pathogens oftentimes goes unnoticed due to the activation of our robust immune systems which sequester and control these...
متن کاملShigella hacks host immune responses by reprogramming the host epigenome.
Bacterial pathogens alter host transcriptional programs to promote infection. Shigella OspF is an essential virulence protein with a unique phosphothreonine lyase activity. A new study in The EMBO Journal (Harouz et al, 2014) reveals a novel function of OspF: targeting of heterochromatin protein 1γ (HP1γ) and downregulation of a subset of immune genes. These results illustrate how bacterial pat...
متن کاملWorming into the cell: viral reproduction in Caenorhabditis elegans.
V iruses, which infect a myriad of cell types from bacteria to mammalian cells, are the ultimate parasites. Upon infection of a host cell, these entities replicate their genetic material, express the proteins required to form mature viral particles, and exit the cell to initiate a subsequent round of infection. At all of these stages, viruses rely heavily on host resources and factors. It is, t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 2014
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.345.6192.43-f