Clinical, Endoscopic and Histopathological Study of Helicobacter pylori Related Gastritis in Adults Tertiary Care Teaching Hospital

Introduction: Helicobacter pylori are major etiological factor in the development of peptic ulcer disease. Aim and Objective: To fi nd out the association of H. pylori with gastric lesions in endoscopic biopsy specimen in semi-urban regions, and to study the specifi city and sensitivity of rapid urease test (RUT), to evaluate the usefulness of Giemsa stain in addition to histopathological examination for identifi cation of H. pylori. Materials and Methods: A prospective study of 50 adult patients presenting with upper abdominal pain, dyspepsia, vomiting, and hematemesis is undertaken to evaluate the relationship of this symptom complex to infl ammatory gastroduodenal lesions with special reference to H. pylori infection. The clinical, endoscopic fi ndings, RUT and histopathological evaluation of gastric antral specimen with special stains to demonstrate the organism are presented and analyzed.