Myocardin is Differentially Required for the Development of Smooth Muscle Cells 1 and Cardiomyocytes 2

Myocardin is Differentially Required for the Development of Smooth Muscle Cells 1 and Cardiomyocytes 2 Mark H. Hoofnagle, Ronald L. Neppl, Erica L. Berzin, G.C. Teg Pipes, Eric N. 3 Olson, Brian W. Wamhoff, Avril V. Somlyo, Gary K. Owens. 4 5 Department of Molecular Physiology and Biological Physics, University of Virginia, 6 Charlottesville, VA 22908, USA 7 Robert M. Berne Cardiovascular Research Center, University of Virginia, 8 Charlottesville, VA 22908, USA 9 Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, 10 Boston, MA 02115 11 12 Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA 13 Metabolic Pathways Center for Excellence in Drug Discovery, GlaxoSmithKline 14 Pharmaceuticals, King of Prussia, PA, 19406 15 16 Department of Molecular Biology, University of Texas Southwestern Medical Center, 17 6000 Harry Hines Blvd., Dallas, TX 75390, USA 18 Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA 19 20 These authors contributed equally to this study. 21