The biomechanics of Wolff's law: recent advances.

نویسندگان

  • P J Prendergast
  • R Huiskes
چکیده

"Wolff's law" is widely known in orthopaedics. For example, it is often said that load bearing devices, such as joint replacement prostheses or external fixators, cause bone to adapt according to Wolff's law. In this article, the scientific basis for Wolff's law is described in the light of recently developed biomechanical theories of bone behaviour.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone.

Bone tissue forms and is remodeled in response to the mechanical forces that it experiences, a phenomenon described by Wolff's Law. Mechanically induced formation and adaptation of bone tissue is mediated by bone cells that sense and respond to local mechanical cues. In this review, the forces experienced by bone cells, the mechanotransduction pathways involved, and the responses elicited are c...

متن کامل

The mechanical properties of trabecular bone: dependence on anatomic location and function.

In 1961, Evans and King documented the mechanical properties of trabecular bone from multiple locations in the proximal human femur. Since this time, many investigators have cataloged the distribution of trabecular bone material properties from multiple locations within the human skeleton to include femur, tibia, humerus, radius, vertebral bodies, and iliac crest. The results of these studies h...

متن کامل

Relevance of collagen piezoelectricity to "Wolff's Law": a critical review.

According to "Wolff's Law", bone is deposited and reinforced at areas of greatest stress. From a clinical perspective, this "law" is supported by the strong association between bone density and physical activity. From a mechanistic standpoint, however, the law presents a challenge to scientists seeking to understand how osteocytes and osteoblasts sense the mechanical load. In the 1960s, collage...

متن کامل

Determination of hip-joint loading patterns of living and extinct mammals using an inverse Wolff's law approach.

It is well known that bone adapts its microstructure in response to loading. Based on this form-follows-function relationship, we previously developed a reverse approach to derive joint loads from bone microstructure as acquired with micro-computed tomography. Here, we challenge this approach by calculating hip-joint loading patterns for human and dog, two species exhibiting different locomotio...

متن کامل

BoneCreo: a novel approach for generating a geometric model of the bone structure.

Bones, the fundamental part of the skeleton, are constantly subjected to many biological processes including growth, feeding and remodelling. Remodelling causes changes in bone structure that may be difficult to notice on a day-to-day basis but become significant over the longer time span. It acts on the cancellous and cortical bone tissue, causing alterations in thickness and spatial arrangeme...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Irish journal of medical science

دوره 164 2  شماره 

صفحات  -

تاریخ انتشار 1995