RUNING HEAD: Trigeminal processing of facial itch and pain
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چکیده
1 TITLE: Facial injections of pruritogens or algogens elicit distinct behavior responses in rats and 2 excite overlapping populations of primary sensory and trigeminal subnucleus caudalis neurons 3 4 5 AUTHORS: Amanda Klein, Mirela Iodi Carstens, E. Carstens 6 7 AFFILIATION: Department of Neurobiology, Physiology, and Behavior 8 University of California, Davis 9 10 RUNING HEAD: Trigeminal processing of facial itch and pain 11 12 CONTACT INFORMATION: 13 Prof. E. Carstens 14 Department of Neurobiology, Physiology, and Behavior 15 University of California, Davis 16 1 Shields Avenue 17 Davis, Ca 95616 18 Tel: 530-752-7767 19 Fax: 530-752-5582 20 e-mail: [email protected] 21 22 23 Articles in PresS. J Neurophysiol (June 8, 2011). doi:10.1152/jn.00302.2011
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Intradermal cheek injection of pruitogens or algogens differentially elicits hindlimb scratching or forelimb wiping, suggesting that these behaviors distinguish between itch and pain. We studied whether pruritogens and algogens excite separate or overlapping populations of primary afferent and second-order trigeminal neurons in mice. Calcium imaging of primary sensory trigeminal ganglion (TG) c...
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The parafascicular nucleus (PFN) of thalamus, as a supraspinal structure, has an important role in processing of nociceptive information. In addition, μ-opioid receptor contributes to supraspinal modulation of nociception. In the present study, the effects of microinjection of naloxone (a non-specific opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were in...
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تاریخ انتشار 2011