Pattern Discovery from Biological Data

نویسنده

  • Jesmin Nahar
چکیده

Extracting useful information from structured and unstructured biological data is crucial in the health industry. Some examples include medical practitioner’s need to identify breast cancer patient in the early stage, estimate survival time of a heart disease patient, or recognize uncommon disease characteristics which suddenly appear. Currently there is an explosion in biological data available in the data bases. But information extraction and true open access to data are require time to resolve issues such as ethical clearance. The emergence of novel IT technologies allows health practitioners to facilitate the comprehensive analyses of medical images, genomes, transcriptomes, and proteomes in health and disease. The information that is extracted from such technologies may soon exert a dramatic change in the pace of medical research and impact considerably on the care of patients. The current research will review the existing technologies being used in heart and cancer research. Finally this research will provide some possible solutions to overcome the limitations of existing technologies. In summary the primary objective of this research is to investigate how existing modern machine learning techniques (with their strength and limitations) are being used in the indent of heartbeat related disease and the early detection of cancer in patients. After an extensive literature review these are the objectives chosen: to develop a new approach to find the association between diseases such as high blood pressure, stroke and heartbeat, to propose an improved feature selection Jesmin Nahar Central Queensland University, Australia Kevin S Tickle Central Queensland University, Australia A B M Shawkat Ali Central Queensland University, Australia Pattern Discovery from Biological Data DOI: 10.4018/978-1-60960-818-7.ch4.3

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A tree-based approach for motif discovery and sequence classification

MOTIVATION Pattern discovery algorithms are widely used for the analysis of DNA and protein sequences. Most algorithms have been designed to find overrepresented motifs in sparse datasets of long sequences, and ignore most positional information. We introduce an algorithm optimized to exploit spatial information in sparse-but-populous datasets. RESULTS Our algorithm Tree-based Weighted-Positi...

متن کامل

Mining Biological Repetitive Sequences Using Support Vector Machines and Fuzzy SVM

Structural repetitive subsequences are most important portion of biological sequences, which play crucial roles on corresponding sequence’s fold and functionality. Biggest class of the repetitive subsequences is “Transposable Elements” which has its own sub-classes upon contexts’ structures. Many researches have been performed to criticality determine the structure and function of repetitiv...

متن کامل

Pattern Discovery In Biosequences: From Simple To Complex Patterns

In the last years, the information stored in biological data-sets grew up exponentially, and new methods and tools have been proposed to interpret and retrieve useful information from such data. Most biological data-sets contain biological sequences (e.g., DNA and protein sequences). Thus, it is much significant to have techniques available capable of mining patterns from such sequences to disc...

متن کامل

The False Discovery Rate in Simultaneous Fisher and Adjusted Permutation Hypothesis Testing on Microarray Data

Background and Objectives: In recent years, new technologies have led to produce a large amount of data and in the field of biology, microarray technology has also dramatically developed. Meanwhile, the Fisher test is used to compare the control group with two or more experimental groups and also to detect the differentially expressed genes. In this study, the false discovery rate was investiga...

متن کامل

Pattern Discovery from Biosequences

In this thesis we have developed novel methods for analyzing biological data, the primary sequences of the DNA and proteins, the microarray based gene expression data, and other functional genomics data. The main contribution is the development of the pattern discovery algorithm SPEXS, accompanied by several practical applications for analyzing real biological problems. For performing these bio...

متن کامل

Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016