Novel MSH2 Mutation in the First Report of a Vietnamese–American Kindred with Lynch Syndrome
نویسندگان
چکیده
•First report of Lynch syndrome in a Vietnamese kindred•A novel MSH2 mutation has been identified.•Culturally sensitive screening programs need to be developed in this growing population.
منابع مشابه
Novel germline MSH2 mutation in lynch syndrome patient surviving multiple cancers
Lynch syndrome (LS) individuals are predisposed to a variety of cancers, most commonly colorectal, uterine, urinary tract, ovarian, small bowel, stomach and biliary tract cancers. The risk of extracolonic manifestations appears to be highest in MSH2 mutations carriers.We present a carrier case with a novel MSH2 gene mutation that clearly demonstrates the broad extent of LS phenotypic expression...
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عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2015