Perspectives International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consensus response criteria in advanced systemic mastocytosis
نویسندگان
چکیده
Stanford University School of Medicine, Stanford, CA; Mayo Clinic, Rochester, MN; Harvard Medical School and Brigham and Women’s Hospital, Boston, MA; III. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany; Centre National de Recherche Scientifique Unité Mixte de Recherche 8147 and Necker Hospital, Paris Descartes University, Paris, France; University Medical Centre Groningen, Groningen, The Netherlands; University of Cologne, Cologne, Germany; Medical University of Vienna, Vienna, Austria; Biederstein Technical University, Munich, Germany; Virginia Commonwealth University, Richmond, VA; Universidad de Salamanca, Salamanca, Spain; Dana Farber Cancer Institute, Boston, MA; Laboratoire Central d’Hématologie, Groupe
منابع مشابه
Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal.
Mast cell leukemia (MCL), the leukemic manifestation of systemic mastocytosis (SM), is characterized by leukemic expansion of immature mast cells (MCs) in the bone marrow (BM) and other internal organs; and a poor prognosis. In a subset of patients, circulating MCs are detectable. A major differential diagnosis to MCL is myelomastocytic leukemia (MML). Although criteria for both MCL and MML hav...
متن کاملماستوسیتوزیس و بهترین شیوه‌های درمانی آن
Mastocytosis most frequently manifests in the skin, so most often is diagnosed by dermatologists at first. Low threshold in clinical suspicion helps early detection of these cases. Cutaneous mastocytosis is an increase of cutaneous mast cells without known underlying disease or inflammatory infiltrate. A skin biopsy with staining specific for mast cells (toluidine blue, Wright-Giemsa) and trypt...
متن کاملImpact of centralized evaluation of bone marrow histology in systemic mastocytosis.
BACKGROUND Bone marrow (BM) histology/immunohistochemistry, KIT D816V mutation analysis and serum tryptase measurements are mandatory tools for diagnosis of systemic mastocytosis (SM). MATERIALS AND METHODS Within the 'German Registry of Disorders on Eosinophils and Mast Cells', we identified 65 patients with SM who had two consecutive BM biopsies. The first biopsy was evaluated by a local pa...
متن کاملClassification and response criteria in mast cell disorders: time to revise?
of mast cell disorders [8, 9] . Since then, the prognostic significance and value of this classifi cation have been confirmed in diverse observational and clinical studies [10–12] . Later, in 2005, the EU-US Consensus Group also defined response criteria for indolent and aggressive disease variants [13] and refined the classification proposal [14] . In 2008, an updated version of the WHO classi...
متن کاملClassification and Response Criteria in Mast Cell Disorders: Time to Revise?
of mast cell disorders [8, 9] . Since then, the prognostic significance and value of this classifi cation have been confirmed in diverse observational and clinical studies [10–12] . Later, in 2005, the EU-US Consensus Group also defined response criteria for indolent and aggressive disease variants [13] and refined the classification proposal [14] . In 2008, an updated version of the WHO classi...
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تاریخ انتشار 2013