duplication internal tandem FLT 3 mutation , but not associated with NRAS with of acute myeloid leukemia patients with poor - risk karyotype associated ) allele is over - represented in a sub - group Val Cytochrome P 450
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word count: 248 words Total text word count: 2729 words Research grants / funding: The study was funded by the Leukemia Research Fund (grant number 98/35). The AML DNA bank has been supported by the Medical Research Council, the Leukemia Research Fund and the Kay Kendall Leukemia Fund. Scientific Heading: NEOPLASIA Copyright (c) 2002 American Society of Hematology Blood First Edition Paper, prepublished online December 5, 2002; DOI 10.1182/blood-2002-01-0228 only. For personal use at PENN STATE UNIVERSITY on March 1, 2013. bloodjournal.hematologylibrary.org From
منابع مشابه
CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication.
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Analyses of 164 RUNX1 mutations (RUNX1mut) in 147 of 449 patients (32.7%) with normal karyotype or noncomplex chromosomal imbalances were performed. RUNX1mut were most frequent in acute myeloid leukemia French-American-British classification M0 (65.2%) followed by M2 (32.4%) and M1 (30.2%). Considering cytogenetics, RUNX1mut were most frequent in cases with +13 (27 of 30, 90%), whereas frequenc...
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تاریخ انتشار 2002