Plenary Paper Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL
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چکیده
Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL Eduardo M. Rego, Haesook T. Kim, Guillermo J. Ruiz-Argüelles, Maria Soledad Undurraga, Maria del Rosario Uriarte, Rafael H. Jacomo, Homero Gutiérrez-Aguirre, Raul A. M. Melo, Rosane Bittencourt, Ricardo Pasquini, Katia Pagnano, Evandro M. Fagundes, Maria de Lourdes Chauffaille, Carlos S. Chiattone, Lem Martinez, Luis A. Meillón, David Gómez-Almaguer, Hau C. Kwaan, Javier Garcés-Eisele, Robert Gallagher, Charlotte M. Niemeyer, Stanley L. Schrier, Martin Tallman, David Grimwade, Arnold Ganser, Nancy Berliner, Raul C. Ribeiro, Francesco Lo-Coco, Bob Löwenberg, and Miguel A. Sanz
منابع مشابه
The results of the International Consortium on Acute Promyelocytic Leukemia: a 'proof of concept' of networking as a strategy to improve the outcome of treatment of hematological malignancies in developing countries
DOI: 10.5581/1516-8484.20130001 On January 14th 2013, the results of the International Consortium on Acute Promyelocytic Leukemia (IC-APL)(1) were published online in the journal Blood. Eight Brazilian institutions participated in the IC-APL: the Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP) as coordinator, the Hematology Divisions of the Universidades Federal do Rio ...
متن کاملImproving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL.
Thanks to modern treatment with all-trans retinoic acid and chemotherapy, acute promyelocytic leukemia (APL) is now the most curable type of leukemia. However, this progress has not yielded equivalent benefit in developing countries. The International Consortium on Acute Promyelocytic Leukemia (IC-APL) was established to create a network of institutions in developing countries that would exchan...
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Background: The secondary genetic changes other than the promyelocytic leukemia-retinoic acid receptor (PML-RARA) fusion gene may contribute to the acute promyelocytic leukemogenesis. Chromosomal alterations and mutation of FLT3 (FMS-like tyrosine kinase 3) tyrosine kinase receptor are the frequent genetic alterations in acute myeloid leukemia. However, the prognostic significance of FLT3 mutat...
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Acute promyelocytic leukemia (APL), a relatively rare hematologic malignancy, is highly curable with current treatment strategies. However, these strategies may be unavailable in countries with limited resources. A review of records in several Latin American countries revealed that approximately 30% of deaths among children and adults with APL were caused by early complications associated with ...
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Background: Due to the estrogen participation in modulating the proliferation and commitment of stem cells and the effects of miR-21 and miR-155 expression on reduced proliferation and colony formation of acute myeloid leukemia (AML), the aim of the present study was to evaluate the effect of estradiol on expression of miR-21 and miR-155 in the NB4 cell line, as an acute promyelocytic leukemia ...
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تاریخ انتشار 2013