PRP in Facial Rejuvenation (Facts vs. Hypothesis)

Ageing is accompanied by a decline in the homeostatic and regenerative capacity of all tissues and organs. Biostimulation for new collagen, elastin, extrafibrillar matrix and vascular network formation has the potential to restructure the skin and reverse the signs of aging [1]. In facial rejuvenation, dermal stimulation and augmentation represent the main facial target in aesthetic medicine. There are numerous exogenous fillers that may be used to obtain a fibrotic response at the dermal level, resulting in volume augmentation and rejuvenation [2]. Platelets in platelet-rich plasma (PRP) act as a storage pool for a vast number of growth factors. Once platelets are activated, growth factors are released in specific ratios and work in a specific order [3].