Case Report of a Pituitary Macroadenoma Treated With Artemether Artemether and Pituitary Macroadenoma
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چکیده
with radiation) is the most common treatment option. Treatment of adenomas with surgery alone is associated with a 9% risk of significant complications other than hypothyroidism. Additionally, there is a significant recurrence risk with surgical treatment alone. Park et al found a 5-year recurrence rate of 15.2% and a 10-year recurrence rate of 50.5% for 132 patients having nonfunctioning macroadenoma who were followed up after treatment by surgical resection alone. Dekkers et al found an approximately 10% recurrence in 99 patients having surgical resection of nonfunctioning macroadenomas after a 6-year follow-up. A combination of surgery and radiotherapy results in a progression-free survival rate of up to 86% in adults. Recurrence of tumor (recurrence of visual symptoms) Introduction: This report describes the case of a male patient with pituitary macroadenoma treated with the artemisinin analog artemether. Patient and Methods: A 75year-old male patient presented with vision, hearing, and locomotion-related problems. Artemether was administered orally to the patient over a period of 12 months. Results: Although the tumor remained consistent in size, CT scan shows a reduction in its density, and clinically, the related symptoms and signs resolved significantly as therapy progressed. Discussion: Overall, the artemether treatment was beneficial in improving the patient’s quality of life. Artemether and other artemisinin analogs offer promise for cancer therapy.
منابع مشابه
Case report of a pituitary macroadenoma treated with artemether.
INTRODUCTION This report describes the case of a male patient with pituitary macroadenoma treated with the artemisinin analog artemether. PATIENT AND METHODS A 75 year-old male patient presented with vision, hearing, and locomotion-related problems. Artemether was administered orally to the patient over a period of 12 months. RESULTS Although the tumor remained consistent in size, CT scan s...
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تاریخ انتشار 2006