Ocular adnexal lymphoma: a review of clinicopathologic features and treatment options.
نویسندگان
چکیده
The recent literature shows that interest in ocular adnexal lymphomas and their biologic and clinical characteristics--along with their possible association with Chlamydia psittaci infection and therapeutic management with rituximab or anti-Chlamydia psittaci antibiotic therapy--is considerable. These new data have modified the previously reported features of this disease and have made an updated review of the literature necessary. The aims of this review are to present the current knowledge on the biology of these lymphomas, their clinical features and prognostic factors, and the panel of all available treatment options.
منابع مشابه
Extranodal marginal zone lymphoma of the ocular adnexa.
Lymphomas of the ocular adnexa are a heterogeneous group of malignancies, composing approximately 1% to 2% of non-Hodgkin lymphomas (NHLs) and 8% of extranodal lymphomas. The most common subtype, accounting for up to 80% of cases of primary ocular adnexal lymphoma, is marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) type. In the recent past, there have been significant advance...
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1. Janatpour KA, Choo PH, Lloyd WC III. Primary orbital peripheral T-cell lymphoma: histologic, immunophenotypic, and genotypic features. Arch Ophthalmol. 2007;125(9):1289-1292. 2. Woog JJ, Kim Y-D, Yeatts RP, et al. Natural killer/T-cell lymphoma with ocular and adnexal involvement. Ophthalmology. 2006;113(1):140-147. 3. Coupland SE, Foss HD, Assaf C, et al. T-cell and T/natural killer-cell ly...
متن کاملTreatment options for ocular adnexal lymphoma (OAL)
Most lymphomas that involve the ocular adnexal structure are low grade, B cell, non-Hodgkin's lymphomas. The treatment depends upon the grade and stage of the disease. High grade lymhoma requires treatment with systemic chemotherapy whereas the localized low grade (extranodal marginal zone lymphoma) can be successfully managed with local radiotherapy. Chlamydia psittaci infection is associated ...
متن کاملOcular Lymphoma: Clinical, Diagnostic, and Therapeutic Aspects
Ocular involvement in lymphoma is a relatively rare condition that can result from a primary intraocular lymphoma or an intraocular manifestation of systemic lymphoma. Lymphoma manifestations frequently masquerade as other more benign intraocular conditions including allergic or infectious conjunctivitis, uveitis, multiple evanescent white dot syndrome, acute retinal necrosis, or herpetic retin...
متن کاملClinicopathologic Study of Chromosomal Aberrations in Ocular Adnexal Lymphomas of Korean Patients
PURPOSE The incidence and clinical correlation of MALT1 translocation and chromosomal numerical aberrations in Korean patients with ocular adnexal mucosa associated lymphoid tissue (MALT) lymphoma have not yet been reported. We investigated the incidence and clinicopathologic relationship of these chromosomal aberrations in ocular adnexal MALT lymphomas in a Korean population. METHODS Thirty ...
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عنوان ژورنال:
- Blood
دوره 108 5 شماره
صفحات -
تاریخ انتشار 2006