Tempering Temperature Changes for Robust Development
نویسنده
چکیده
Developmental signaling pathways needed to evolve to be robust against environmental fluctuations. In this issue, Shimizu et al. reveal a complex system of interacting endocytic pathways that help to maintain consistent levels of Notch activity across a range of temperatures.
منابع مشابه
Effect of Heat Treatment Process on the Fatigue Behavior of AISI 1060 Steel
This experimental study investigated the effects of quenching and tempering heat treatment on fatigue behavior and also tempering temperature and time holding of AISI 1060 steel. At first, the specimens were austenitized at 800˚C for 1 hour, and then were quenched in the water bath of 25˚C temperature. After that, tempering process was done at the temperature of 250˚C, 450˚C and 650˚C for 1 and...
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The present paper explores a simple approach to the question of parallel tempering temperature selection. We argue that to optimize the performance of parallel tempering it is reasonable to require that the increase in entropy between successive temperatures be uniform over the entire ensemble. An estimate of the system's heat capacity, obtained either from experiment, a preliminary simulation,...
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متن کاملPhase changes in 38-atom Lennard-Jones clusters. I. A parallel tempering study in the canonical ensemble
The heat capacity and isomer distributions of the 38-atom Lennard-Jones cluster have been calculated in the canonical ensemble using parallel tempering Monte Carlo methods. A distinct region of temperature is identified that corresponds to equilibrium between the global minimum structure and the icosahedral basin of structures. This region of temperatures occurs below the melting peak of the he...
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عنوان ژورنال:
- Cell
دوره 157 شماره
صفحات -
تاریخ انتشار 2014