Underwriting Adult Polycystic Kidney Disease (APKD)
نویسنده
چکیده
In adult polycystic kidney disease (APKD), the cysts begin as tiny vesicles involving only one to two percent of the renal tubules.1 These "renegade" nephrons enlarge slowly but progressively, compressing and virtually obliterating the normal parenchyma, ultimately inducing renal insufficiency. This deterioration in function appears to accelerate in later life. A mathematical model of spherical enlargement has been proposed wherein further increments in cyst radius impose a proportionately greater displacement of contiguous normal nephrons.2
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Nefro - 24-2 - MIOLO.indd
There is a dearth of information on the prevalence and clinical characteristics of adult polycystic kidney disease (APKD) in Nigeria. Earlier studies in the tropical developing countries have reported either the rarity or very low prevalence of this disease and more importantly as a cause of renal failure, but there are hardly any such studies focussing on the pattern of APKD in renal disease p...
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متن کاملMicrosoft Word - NEF318BF
Dr. Piero Dionisio, Department of Nephrology, Ospedale degli Infermi, via Caraccio n. 5, I-13051 Biella (Italy) Dear Sir, Montoyo et al. [1] have recently described a case of nephrotic syndrome (NS) and focal glomerulosclerosis (FGS) in a young 35-year-old man affected by adult polycystic kidney disease (APKD). According to Montoyo et al. and to our experience moderate proteinuria is observed i...
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تاریخ انتشار 2005