Complete spontaneous regression of a metastatic acral melanoma with associated leukoderma
نویسندگان
چکیده
C utaneous melanoma (CM) is the leading cause of skin cancer mortality worldwide despite constituting only 4% of skin cancers. Acral melanoma (AM) is a distinct variant of CM and is generally associated with a poor prognosis. Complete spontaneous regression of CM is a rare but well described phenomenon. We present an unusual case of a complete spontaneously regressed metastatic AM with melanoma-associated leukoderma.
منابع مشابه
Complete spontaneous regression of pulmonary metastatic melanoma.
BACKGROUND Complete spontaneous regression of melanoma metastatic to the lungs is a rare event. OBJECTIVE To report a case of biopsy-proven melanoma metastatic to the lung with complete spontaneous regression. METHODS Multidisciplinary case report. RESULTS A 35-year-old white female was diagnosed with metastatic melanoma to the lung. A pleural biopsy confirmed the diagnosis. Partial spont...
متن کاملImmunotherapy-induced leukoderma from treatment of melanoma with IL-2: a case report and a review of the literature.
Melanoma-associated leukoderma (MAL) is a relatively uncommon phenomenon in the literature that can present (1) before melanoma detection, (2) after detection and before treatment, and (3) after treatment with immunotherapeutic agents. We report a case of MAL in an 83-year-old man after treatment with high dose IL-2 for metastatic melanoma and further describe the literature of the underlying m...
متن کاملMalignant Melanoma in Khouzestan: Study of 62 cases
Background: Malignant melanoma is the leading cause of death among skin cancers in western countries. However, the incidence, histologic subtypes, and tumor behaviors are quite different in Asians and western populations. Objective: This study was designed to survey the clinicopathological aspects of malignant melanoma among Khouzestan people. Patients and Methods: In a retrospective stud...
متن کاملMetastatic melanoma with spontaneous complete regression of a thick primary lesion
Fig 1. Left side of the chest skin biopsy for primary malignant melanoma. Histopathologic examination found a thick primary melanoma characterized by atypical pigmented epithelioid cells with extensive ulceration. INTRODUCTION Spontaneous regression of malignant melanoma is defined by the disappearance of melanocytic neoplastic cells partially or completely. In contrast to the partial form, com...
متن کاملEfficacy of BRAF Inhibitors in Asian Metastatic Melanoma Patients: Potential Implications of Genomic Sequencing in BRAF-Mutated Melanoma12
BACKGROUND The BRAF inhibitors vemurafenib and dabrafenib are currently the standard treatment for metastatic melanoma with BRAF V600 mutations. However, given the rarity of noncutaneous melanoma, including acral and mucosal subtypes, the efficacy of BRAF inhibitors for this subset of patients has not been extensively investigated. Acquired resistance generally appears 6 to 8 months after treat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2017