Modeling Sensitization to Stimulants in Humans An [C]Raclopride/Positron Emission Tomography Study in Healthy Men
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چکیده
Context: In animals, repeated exposure to stimulant drugs leads to an enhanced drug-induced psychomotor response and increased dopamine release. This phenomenon, known as sensitization, may confer vulnerability to drug addiction or drug-induced psychosis in humans. A similar phenomenon, referred to as endogenous sensitization, is also believed to play a role in the emergence of positive symptoms in patients with schizophrenia.
منابع مشابه
Modeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men.
CONTEXT In animals, repeated exposure to stimulant drugs leads to an enhanced drug-induced psychomotor response and increased dopamine release. This phenomenon, known as sensitization, may confer vulnerability to drug addiction or drug-induced psychosis in humans. A similar phenomenon, referred to as endogenous sensitization, is also believed to play a role in the emergence of positive symptoms...
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تاریخ انتشار 2006