Commentary on significance of positive surgical margins. - PubMed - NCBI
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Prognostic Value of Focal Positive Surgical Margins After Radical Prostatectomy. - PubMed - NCBI
The data were analyzed retrospectively for 1733 patients with clinically localized prostate cancer who had undergone RP at our institution from December 2003 to March 2014 without neoadjuvant or adjuvant therapy. Positive surgical margins were characterized as FPMs (≤ 3 mm long) or non-FPMs (> 3 mm long). Multivariate analysis of the clinicopathologic factors, including FPMs, was performed with...
متن کاملDo margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. - PubMed - NCBI
The prognostic significance of positive surgical margins (PSM) in radical prostatectomy (RP) specimens remains unclear. While most studies have concluded that a PSM is an independent adverse prognostic factor, others report that surgical margin status has no effect on prognosis. One reason for these discordant conclusions is the variable number of patients with a PSM who receive adjuvant therap...
متن کامل[Positive surgical margins after radical prostatectomy]. - PubMed - NCBI
Abstract Positive surgical margins (PSMs) in radical prostatectomy specimens are usually considered a negative prognostic parameter. However, their definition and the management of patients with PSMs remain unclear. The aim of the present review is to define pathological features of PSMs,to report their incidence and risk factors and to update PSMs prognostic meaning and possible treatment moda...
متن کاملCorrelation between prolonged use of aspirin and prognostic risk in... - PubMed - NCBI
Aims and background. In recent years the role of inflammation in cancer etiology has gained attention and several studies have suggested that acetylsalicylic acid and other nonsteroidal anti-inflammatory drugs may have chemopreventive activity and reduce the risk of prostate cancer. We investigated whether there is a correlation between prolonged use of aspirin and prognostic risk in prostate c...
متن کاملPositive surgical margins after radical prostatectomy: a systematic review and contemporary update.
CONTEXT The clinical significance of positive surgical margins (PSMs) in radical prostatectomy (RP) specimens and the management of affected patients remain unclear. OBJECTIVE To address pitfalls in the pathologic interpretation of margin status; provide an update on the incidence, predictors, and long-term oncologic implications of PSMs in the era of robot-assisted laparoscopic RP (RALRP); a...
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تاریخ انتشار 2016