VIII. Mutations of the hisT Gene

نویسندگان

  • GEORGE W. CHANG
  • JOHN R. ROTH
چکیده

The hisT gene, one of six genes in which mutation causes derepression of the histidine operon in Salmonella typhimurium, is shown to code for a protein that is not essential for the growth of the bacteria. This is indicated by the characterization of particular classes of mutations in the hisT gene: amber mutations, frameshift mutations, and temperature-sensitive mutations that affect repression but not growth. In addition, the class of semilethal mutations was selected for but not found.

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تاریخ انتشار 2003