Patterned multiplex pathogen DNA detection by Au particle-on-wire SERS sensor.
نویسندگان
چکیده
A Au particle-on-wire system that can be used as a specific, sensitive, and multiplex DNA sensor is developed. A pattern formed by multiple Au nanowire sensors provides positional address and identification for each sensor. By using this system, multiplex sensing of target DNAs was possible in a quantitative manner with a detection limit of 10 pM. Target DNAs from reference bacteria and clinical isolates were successfully identified by this sensor system, enabling diagnostics for infectious diseases.
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عنوان ژورنال:
- Nano letters
دوره 10 4 شماره
صفحات -
تاریخ انتشار 2010