Pii: S1010-7940(99)00184-0

Objectives: To demonstrate the ef®cacy of using thoracoscopic endoloop ligation of bullae in patients with bullous emphysema. Methods: From 1992 to 1997, 93 advanced age (mean age, 66 years) and oxygen dependency patients underwent thoracoscopic procedure using endoloop ligation for treatment of bullous emphysema. Clinical data were collected from chart review. Thoracoscopic loop ligation of bulla was carried out under general anesthesia with double lumen endotracheal tube and single lung ventilation. Results: Eighty-two patients (88%) exhibited subjective improvement in their symptom status at 3-month follow-up (from grade 2 or 3 to grade 1 or 2) according to the modi®ed Medical Research Council dyspnea scale. The mean duration of chest drainage was 7.5 days (range, 4±19 days). Average hospital stay was 9.5 (range, 5±26) days. There was no post-operative death. A comparison of pre-operative and post-operative functional evaluation was available in 27 patients who showed an average increase in FEV1 (from 0.89 to 1.12 l) and declined in residual volume after operation. Complications include persistent airleak over 10 days in nine patients (9.7%), wound infection in three patients and localized empyema in ®ve patients. There was no recurrent after a mean follow-up of 37 months. Conclusion: Thoracoscopic loop ligation of bulla has proven to be a safe, reliable and cost effective means of technique for bullous emphysema. q 1999 Elsevier Science B.V. All rights reserved.