Cost-effectiveness of percutaneous radiofrequency ablation for malignant hepatic neoplasms

Health technology The health technology examined in the study was radiofrequency (RF) ablation, a minimally invasive technique for the treatment of malignant liver neoplasms, in particular hepatocellular carcinoma (HCC) and colorectal liver metastases (CLM). Percutaneous RF ablation involves the insertion of one or more electrodes into the tumour nodule under imaging guidance. A high-frequency alternating electrical current is then applied and increased temperatures initiate protein denaturation. This strategy reduces the need for an open procedure and can easily be performed on an outpatient basis.