Membrane Curvature in Synaptic Vesicle Fusion and Beyond

نویسندگان

  • Harvey T. McMahon
  • Michael M. Kozlov
  • Sascha Martens
چکیده

Recent evidence suggests that the Ca(2+)-sensors synaptotagmin-1 and Doc2b deform synaptic membranes during synaptic vesicle exocytosis. We discuss how local curvature generated by these and other proteins may stimulate membrane fusion and discuss the potential implications of these findings for other cellular fusion events.

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عنوان ژورنال:
  • Cell

دوره 140  شماره 

صفحات  -

تاریخ انتشار 2010