Structures and anti-cancer properties of two binuclear copper complexes.
نویسندگان
چکیده
The crystals of two binuclear copper-based complexes were obtained. One complex can remarkably induce apoptosis and inhibit angiogenesis to mediate tumour growth at a greater extent. Furthermore, this complex showed a strong energy-dependent and non-endocytotic uptake and exhibited multiple anti-cancer functions by inhibiting the expressions of p-Akt and p-Erk1/2 proteins and by decreasing the levels of reactive oxygen species.
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عنوان ژورنال:
- Dalton transactions
دوره 42 41 شماره
صفحات -
تاریخ انتشار 2013