Terminology for red cell antigens-1999 update.

CAR T-cell Therapy of Hematologic Malignancies: An Update in Targeted Antigens

Immunotherapy with genetically engineered T-cells that express the chimeric antigen receptor (CAR) has raised hopes for the treatment of pediatric malignancies. Although CAR T-cell development is on a fast-moving pace and evolution, the context of exploring novel targetable antigens has been neglected. In this review study, we analyze the prominent hematologic antigens targeted by engineered T-...

Prevalence of Alloantibodies and Autoantibodies in Transfusion Dependent Thalassemia Patients

Background: The development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. Also, Autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. We studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in Ilam province...

ISBT working party on terminology for red cell surface antigens. Preliminary report.

ISBT Working Party on Terminology for Red Cell Surface Antigens: Munich report.

The ISBT Working Party on Terminology for Red Cell Surface Antigens was established in 1980 under the chairmanship of Dr. F.H. Allen, Jr., to devise a numerical nomenclature suitable for computerization. The intent is to provide a standard terminology for those who care to use it, not to replace existing alphabetical symbols. The Working Party is also charged with maintaining uniformity in alph...

Blood groups: In Health and Diseases

ABO blood type antigens are polymorphic, inherited structures presented on the surface of red blood cells. Although ABO blood group antigens is the most important antigens in transfusion medicine, its main role is not clearly clarified. Correlation between ABO blood group and susceptibility to certain infectious and non-infectious diseases is a controversial issue. Since, lack of blood type ant...