Coenzyme A Reductase Inhibition With Cerivastatin in Rats With Heart Failure After Improvement of Left Ventricular Remodeling and Function by Hydroxymethylglutaryl
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Myocardial Infarction Coenzyme A Reductase Inhibition With Cerivastatin in Rats With Heart Failure After Improvement of Left Ventricular Remodeling and Function by Hydroxymethylglutaryl Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2001 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/hc3401.095946 2001;104:982-985 Circulation. http://circ.ahajournals.org/content/104/9/982 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction.
BACKGROUND Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) attenuate angiotensin II-induced cellular signaling. Because angiotensin II is involved in left ventricular (LV) remodeling after myocardial infarction (MI), we examined the effects of statin treatment in an experimental model of chronic heart failure after MI. METHODS AND RESULTS Rats with extensive MI were treated wi...
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Abstract Background; the MYH7 and MYH7b genes have important role on heart function on other hand endurance training is a challenge for heart function, therefore the aim this study was to study The effect of endurance training[a2] on Change of MYH7and MYH7b genes expression and left ventricular structural changes of wistar male rats. Material and Methods; For this purpose, 14 rats (113±20...
متن کاملFluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction.
BACKGROUND Short-term administration of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, statins, has been shown to attenuate ischemia-reperfusion injury. However, the effects of long-term administration of statins on left ventricular (LV) remodeling and failure after myocardial infarction remain unknown. METHODS AND RESULTS Mice were subjected to coronary artery ligation...
متن کاملCerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
BACKGROUND The short-term effects of hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) on endothelial function at doses that do not affect plasma lipid levels are not known. METHODS AND RESULTS We investigated the short-term effects of cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, on endothelial function and endothelium-related products in elderly diabeti...
متن کاملNew manifestations of electrophysiological remodeling of heart during experimental model of atrial fibrillation in cirrhotic rat isolated heart
Introduction: The present study is aimed to evaluate electrophysiological remodeling of atrioventricular (AV) node and ventricular conduction during experimental atrial fibrillation (AF) model in isolated heart of cirrhotic rats. Methods: Cirrhosis-induced electrophysiological remodeling was evaluated in 24 isolated retrogradely perfused rat hearts in 2 groups (control and cirrhotic). Cirrho...
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تاریخ انتشار 2001