A 2-year study of the efficacy and tolerability of prenylamine in the treatment of angina pectoris.

Twelve out-patients with established angina pectoris who had previously participated in a double-blind trial of prenylamine lactate continued to record their daily anginal attack rate and glyceryl trinitrate consumption over the subsequent 18 months. The improvement noted while taking prenylamine during the trial was maintained and a further double-blind study confirmed that this was, in fact, due to the administration of the drug, which was again shown to be significantly more effective than identical placebo in the prophylaxis of angina pectoris.