BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data
نویسندگان
چکیده
UNLABELLED Despite recent progress, computational tools that identify gene fusions from next-generation whole transcriptome sequencing data are often limited in accuracy and scalability. Here, we present a software package, BreakFusion that combines the strength of reference alignment followed by read-pair analysis and de novo assembly to achieve a good balance in sensitivity, specificity and computational efficiency. AVAILABILITY http://bioinformatics.mdanderson.org/main/BreakFusion
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عنوان ژورنال:
- Bioinformatics
دوره 28 14 شماره
صفحات -
تاریخ انتشار 2012